Botox/Dysport - Related Questions

Q. Is it ever possible for Botox to stop working? I found that the last time, it did not take as well. It has been a while since I had it and hoped it would work as well as it used to

A. There are theories that antibodies can form against Botox, but we are not seeing this with usual cosmetic dosages. What I suspect happened with you is that your lines are being etched in deeper with your hiatus from treatment. I would try once more, using a higher dose. Another option is to add filler like Restylane or Juvederm to complement the action of the Botox.

Q. I do not have wrinkles yet. I am only 26 years old, but I have heard Botox can raise the eyebrows. Am I too young to do Botox?

A. You are not too young for Botox. Conservative Botox injections in just the right places, will lift your brows and open up your eyes. Another bonus is that it has a preventative benefit against crow’s feet and frown lines when you do the brow lifting technique.

Q. I went to a medspa and the doctor admitted to me that they save Botox for several days after he mixes the 200 units with 10 cc of saline. I decided against the injection, but does Botox keep that long?

A. You were smart to pass on getting that injection. There is no Botox vial that comes in 200 unit increments. Botox Cosmetic, which is what has been FDA approved for wrinkle reduction in the glabellar frown lines, comes in 50 and 100 unit vials. The usual dilution is 1-2.5cc. So, there is a chance this medspa is importing illegal botulinum toxin and calling it Botox. 10cc is also too much liquid and will result in too much diffusion of product away from the injection site. This increases the chances of eyelid drooping and brow drooping. The real Botox does last several days after mixing, but if you go to a board certified dermatologist who is experienced with the product, a vial rarely lasts longer than a few hours. Botox in the right hands is very popular!


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Lupo Center for Aesthetic and General Dermatology
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Our mission at the Lupo Center is to provide patients with innovative, effective and ethical care to make each person look and feel their personal best. To fulfill our goal, we provide state-of-the-art medical, surgical and cosmetic treatments to all patients.

Board certified dermatologist and clinical professor of dermatology Mary P. Lupo, MD has been a leader in the field of non-surgical rejuvenation since 1983. She travels internationally to teach her innovative techniques, and her reputation brings in patients from around the country. She started the first formal residency training program for injectables and peels in 1983 at Tulane Medical School and served as past president of Women’s Dermatologic Society, adjunct professor of dermatology at Tulane and a founder of Cosmetic Boot Camp. Dr. Lupo holds membership in many prestigious dermatology associations, participates in clinical trials for approval of new drugs and devices and acts as an advisor for numerous aesthetic-minded companies.

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