Jeuveau

Those pesky wrinkles that appear in between your eyebrows, on your forehead or around your eyes can make you look older than you are. Even worse, they can send the signal to others that you are angry or unhappy, no matter how great you are feeling! Fortunately, patients seeking treatment to reduce these wrinkles now have more options than ever before. An exciting new product, Jeuveau, is now offered at the Lupo Center for Aesthetic & General Dermatology in New Orleans, LA. This FDA-approved neuromodulator has been shown to be effective at reducing lines and wrinkles, and Dr. Lupo is fortunate to be one of the earliest adopters of this new treatment by serving as an investigator in the clinical trial.

Dr. Lupo participates in Jeuveau clinical trial

Since 2002 when Botox was first FDA approved, Dr. Mary Lupo has been at the forefront of using neuromodulators, or neuromuscular blocking agents, to relax overactive muscles that cause wrinkles. She has participated in several FDA clinical trials for different uses of neuromodulators, so it was no surprise when the maker of Jeuveau, Evolus, approached her to participate in the FDA approval of their "new tox."

As the only practice in Louisiana to participate in Jeuveau’s clinical trial, Dr. Lupo learned first-hand the best practices for this non-surgical wrinkle reducer. She could see how it compared to other neuromodulators such as Botox, Dysport, and Xeomin, and began to figure out how it would work best for her patients and how to use it in a complementary way with other treatments for overall facial rejuvenation.

“As an FDA clinical trial investigator and an advisory board member for Jeuveau, I know what an amazing product this is for my aesthetic patients,” said Dr. Mary Lupo. “Being a part of clinical research for Jeuveau, as well as Botox, Juvederm, Volbella, and Kybella, helps me provide my patients with the finest care using the latest products and knowing their best application as soon as they are available for clinical use. The comprehensive data generated by Evolus through the clinical program is another reason I’m confident my patients will love Jeuveau!”


Jeuveau at Lupo Center for Aesthetic and General Dermatology

Jeuveau at Lupo Center for Aesthetic and General Dermatology
Reduce your frown lines, crows feet, or headlines with Jeuveau. Watch this video to learn all about it, as Dr. Mary Lupo from Lupo Center for Aesthetic and General Dermatology explains.


What is Jeuveau?

Jeuveau is the newest neuromodulator on the market.

Neuromodulation reduces signaling to the muscles from the nerves, in turn reducing movement-induced lines, folds, and wrinkles.

We also use neuromodulators, commonly called Botox products, to lift the eyebrows, reduce the downward pull along the jawline, and lift the mouth's corner.

What problem areas can Jeuveau fix?

Most of our patients who've tried Jeuveau have found that it's a highly effective product.

It helps reduce frown lines, crows feet, or headlines and lift brows and the corners of the mouth.

It also helps improve the jawline by reducing the pull-down of a muscle in the neck that pulls the jawline downward.

What makes Jeuveau stand out?

Results of Jeuveau in our practice resolve a quicker onset than the other products on the market, and many of our patients found that it lasts a bit longer.

Anywhere from 2- 4 weeks longer. However, individual variability in response to any product can be expected.

The Lupo Center is proud to have been a part of the original clinical trial for FDA approval.

We encourage our patients who have tried other neuromodulators and are not entirely delighted with their results to try Jeuveau and see if it gives them the next level of improvement.

Please feel free to contact us if you need further information.


What makes Jeuveau stand out?

During the clinical trial, the injectable neuromodulator Jeuveau went head to head with Botox, and in great news for patients, the results showed a slightly longer duration of effectiveness. While the duration of the results varies depending on several factors, most patients should see results for three to six months. Factors that can affect how long the results last include:
  • How much muscle mass you have – more muscle means that your body will metabolize the drug more quickly
  • The amount of product used for your needs
  • The location of the treatment – it is important to have a board certified aesthetic physician like Dr. Lupo who knows precisely where to inject the neuromodulator for the best results
Jeuveau, which is also the first aesthetic-only neuromodulator approved by the FDA, is manufactured in a state-of-the-art facility using Hi-Pure technology in order to meet quality standards and to provide patients with the safest and most effective product.

Jeuveau cost

The cost of Jeuveau is similar to other neuromodulators such as Botox, Xeomin, and Dysport. Your total cost will depend on how many injections you need and how much product is used to achieve the results you are seeking. We will discuss the pricing of the treatment with you in advance of the procedure.

Is there pain or downtime?

Patients report little to no pain with Jeuveau treatments. We offer topical numbing prior to the treatment and use very small needles to inject Jeuveau, so the pain you will experience during the procedure is minimized. You may experience some mild discomfort, but most patients say that it feels like a tiny pinch or an acupuncture needle.

The side effects of Jeuveau are typically minor, so there is little to no social downtime after your injections. You may experience some minor bruising, swelling or redness at the injection sites, but those typically fade soon after treatment.

How to choose a neuromodulator?

Just like with any other cosmetic procedure, our board certified dermatologists will evaluate each patient’s unique needs and desires. With ongoing professional trainings, teachings and experience, Dr. Lupo is fully qualified to recommend the best products for a natural, more youthful appearance. We pride ourselves in having the most state-of-the-art injectables, peels, lasers and devices, so patients know when they come to the Lupo Center for Aesthetic and General Dermatology in New Orleans they are receiving the best results for their skin care needs.

Schedule a consultation

Stop letting your wrinkles make you look older than you are or affect your interactions with others. Experience the difference in skin rejuvenation care treatments at the Lupo Center for Aesthetic and General Dermatology by scheduling a consultation one of our board certified dermatologists. Our office can be contacted at (504) 777-3047 or info@drmarylupo.com. We look forward to helping you achieve a more youthful appearance that reflects your true, radiant self!

Related Videos

Non-Surgical Eyebrow Lift

Non-Surgical Eyebrow Lift by Dr. Mary Lupo
Dr. Lupo shows how she carefully individualises a non-surgical eyebrow lift procedure to ensure that her patient receives unique and aesthetically pleasing results.


So during the pandmic and isolation at home, I posted about eyebrow shaping. Now, one of the things that’s important with a patient is to look at their natural brow position. Notice that they are a little too low, also notice that they are asymmetrical and that this goes down too far on this side. So we are going to do a combination of neuromodulator to give her a brow lift but also physically elevate the lateral brow with a filler. And we are going to do this all at the same time. Now this is not meant to be an instruction for everyone. This is a very individualised treatment for this patient and her unique anatomy. So what we have done is we have used the Acuvane to make sure she doesn’t have any big blood vessels where I am going to be going in. So we use this to help us with safety and preventing bruising of our patients. In addition, I always have an assistant who is going to hold pressure immediately after an injection. So, we are going to go ahead and we are just going to inject this side and the neurotoxin on camera and do the other side later so I don’t have to move around as much. So we are going to go in and the most important thing in this area is to do a little bit of a reflux and we are actually going to put a little strip of filler to give a little bit of lift to that lateral eyebrow and then Stacy is going to hold pressure on there for me. Then what we are going to do in this patient’s case is she has very low medial brows. So we want to relax her corrugators and her procerus. So we know that she is got a very strong proseras and make her smell something nasty and she has a very strong nasalis and procerus. Relax. So we are definitely going to inject those areas as well. Because that helps to lift the medial brow in this patient. In addition, we are going to do a little bit of a..We are jusing Jeuveau here because of its precision. I also like Botox and Xeomin for more precise injections. In addition, we are going to put some in the tail of her brow here and we are going to put a little bit in this area here because we noticed earlier that she was stronger on one side than the other. And a little bit higher on this side and then last, we are going to put a little in the tail over here. And by doing it this way, she should notice a lateral eyebrow lift over the next week.

Injectable brow lift with Jeuveau

Injectable brow lift with Jeuveau by Dr. Mary Lupo
If you have eyebrows that make you look concerned or sad, Dr. Lupo shows how these can be corrected with a non-surgical eyebrow lift with fillers.


We have talked before on previous posts about eyebrow shaping and how to prevent the medial brow from being down and giving you an angry look.This patient has the opposite problem. Her medial brows tend to be high and her lateral eyebrows tend to be low. The reason this is not an optimal look, it makes the patient look sad or concerned all the time. So what we want to do for this patient is give her a lateral eyebrow lift and to soften this area here. So we are going to be injecting in three areas but it is all about shaping her eyebrows. Give me a frown. So we are grabbing and we are injecting in the brow depressor. I am going to do the same thing. Frown. And the reason we are doing it this way makes sure that we are lifting it above the orbital rim. Then we are going to do, make a face like you smell something unpleasant. Now we are going to do the depressor which is the procerus so that’s going to soften this area here and in order to get a lateral eyebrow lift we are going to be injecting in the medial forehead. So that we get compensatory strengthening of the lateral forehead and in addition we are going to be injecting the tail of the brow and we are doing that to get a little bit of a lift in addition to from a lateral brow flare. Ok, all done.

Let your kind and happy inner personality shine through with Jeveau treatments

Non Invasive Fillers and Devices for Rejuvenation of the Eyes by Dr. Mary Lupo
Do you have an eternally frowning face or one which always looks rather angry? Do you feel your happy and kind personality is not complemented by your appearance? Dr. Lupo offers Jeuveau treatments to help that beautiful personality shine through, even in men who look angry but truly are not!


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Jeuveau is a multi-purpose filler!

Jeuveau is a multi-purpose filler!
Jeuveau is a versatile treatment that is offered by Dr. Lupo. It is not only used for fine lines around the eyes but can also be used for brow lifts, gummy smiles, chin dimpling and neck banding, among others.


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Smooth forehead with Jeuveau

Smooth forehead with Jeuveau
With age, your facial expressions and movements can leave fine lines and wrinkles etched on your forehead, adding years to your appearance. Dr. Lupo shows how Jeuveau can smooth out your forehead.


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Jeuveau injections to open up your eyes!

Jeuveau injections to open up your eyes! by Dr. Mary Lupo
Dr. Lupo shows how Jeuveau in just two places can make a world of difference to the appearance of your eyes. You can expect to start seeing results within 3 days and full results within a week!


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Neuromodulator for Brow Lift can be achieved with Jeuveau, Botox, Dysport or Xeomin

Neuromodulator for Brow Lift can be achieved with Jeuveau, Botox, Dysport or Xeomin - Dr. Lupo
So, one of the best users of neuromodulators is a brow lift. A lot of people know about using Botox, Jeuveau, Xeomin and Dysport for frown lines and for crow’s feet. But when strategically placed you can also improve the position of the brow....


So, one of the best users of neuromodulators is a brow lift. A lot of people know about using Botox, Jeuveau, Xeomin and Dysport for frown lines and for crow’s feet. But when strategically placed you can also improve the position of the brow. One of the secrets to a proper brow lift is to decrease the injection in the forehead area. Your forehead has the frontalis muscle and the frontalis muscle is essential for lifting the eyebrows. If the frontalis muscle is over injected, the muscle is weakened and the brows will actually go down. I always tell my patients it is better to have a line and get a lift, than to get rid of the line and get a sag. So, what we are going to do is inject a combination of her process… corrugators, crow’s feet and a little bit in the forehead because we want, as you look her brow position is very low here. So, we want to get what is called a lateral eyebrow lift. A lateral eyebrow lift is achieved when you do a little bit in the frontalis and you get compensatory straightening in the lateral frontalis to lift the lateral eyebrow. Some patients need a medial eyebrow lift. That pattern would be different. What I don’t like is when I see people who get Botox and their brows look like this and it makes them look mad of if they are overly sparked. So, it’s all about looking at the muscles and individualizing the treatment for each patient. So, here we go. Give me a big smile. Relax. I notice she has little tiny .. vessels here that indicate where this brow is being pulled down. In addition, we are going to do a little bit here and a little bit here. The lower crow’s feet is the most difficult area to ... with just Botox because the smile muscle pushes and causes some frown, some of these crow’s feet, so when these little frown lines bother a patient, I usually add either a laser or radio frequency device or an ad filler. Frown like a man. Now relax. The .. is an important muscle to inject. And we have to do that because that pulls the medial brow down. Frown like a man. Relax. You want to grab that muscle and you have to get that above the .. to prevent any potential brow drooping. Same thing on this side. Make your face like to smell something nasty. Yes. I think the nasalis should always be treated if they are noticeable. Because if you don’t you get a strengthening and deepening of those lines. Yeah finally, we are going to do a little bit more in the corrugators. Frown like a man. Relax. To get a little bit of it a lateral improvement and this will also help to raise the brows and then finally we are going to put a little in the medial part here so she can get a strengthening and an improvement in her lateral eyebrow.

Neuromodulators such as Jeuveau, Botox, Dysport or Xeomin can relax platysma muscle banding to prevent sagging on the jawline and neck

Neuromodulators such as Jeuveau, Botox, Dysport or Xeomin can relax platysma muscle banding
Another great use of neuromodulators if for the platysmal bands that pull our face down as we age and it gives an unsiding.. banding effect. Go ahead and show us your ugly band. See that ... there, so that’s what we want to get rid of....


Another great use of neuromodulators if for the platysmal bands that pull our face down as we age and it gives an unsiding.. banding effect. Go ahead and show us your ugly band. See that ... there, so that’s what we want to get rid of. You can use Botox, Jeuveau, Xeomin or Dysport for this. ... I like to grab it and inject, grab it, grab it, here we go.. okay.

Live Jeuveau treatment for a chemical brow lift with a neuromodulator

Live Jeuveau treatment for a chemical brow lift with a neuromodulator
So, today I have the pleasure of making beautiful, someone who makes me beautiful by doing my hair. Sarah has been taking care of my hair for probably about 15 years. She does my cut, she does my color, she does my blow ups. So....


So, today I have the pleasure of making beautiful, someone who makes me beautiful by doing my hair. Sarah has been taking care of my hair for probably about 15 years. She does my cut, she does my color, she does my blow ups. So, today she’s here to have Jeuveau and we are going to do a chemical brow lift. The reason I am going to do a chemical brow lift is, Sarah’s very best feature are her beautiful blueish-green eyes. So, when we give her a little bit of a brow lift and she can frown. Frown force as hard, it will open her up and make her.. relaxed and she’ll look happier. So, Sarah tell us what did you notice about Jeuveau when you had it for the first time? Sarah - I noticed less .. and I noticed it was quicker to take effect. So, normally the Botox will be about two weeks, I felt about a week was better. Good, good and did you notice any difference in the effect. Did it look exactly the same? Sarah - I felt it looked exactly the same, I just felt that as I said earlier it took quicker effect. And what about duration? Sarah - It lasted about a month longer, so I had an appointment in set for last month and then rescheduled for this month. So, normally you get four months for Botox? Which is what most people hope to get and you actually got closer to five months with this. Sarah - Yes Okay, so we are going to go ahead and inject Sarah. We are going to start. I call this chemical brow lift and we inject the muscles in the middle that actually push the eyebrow together and down. Go ahead and frown.. See how those eyebrows move down when those muscles are activated and then relaxed. And give me a squinty squinty smile. That pulls this a little bit down too. So, when we do the treatment here and here and in the centre between the brows, she’s going to have an improvement in her frown lines, but the most important thing is that she’s going to get a chemical brow lift. Okay Sarah, go ahead and give me a bigger frown. So, we are going to start by injecting the prosalas muscle, so if you notice, she ... from her nasalas, so we are going to go ahead and inject her nasalas muscle on both sides like that. Then, we are going to go ahead. We did the prosalas and the nasalas, now we are going to do her corrugators, found really really hard, relax.. so what we want to do is actually lift that muscle up above the orbital .. and we want to inject it in the area and in the direction where that muscle moves, which is in this direction. Frown again hard. When they frown, you can grab the muscle  you can pull it up above the orbital .. and you can go ahead safely injecting that area. Then lastly we can go ahead and do something on the lateral brow to give her a little bit of a lift and we are going to do it here, we are going to do it here and we are going to do a little bit down here just to soften the crow’s feet a little bit lower. Okay! and that is it. Sarah, how much did that hurt? Sarah - Not at all Good, we use a little numbing medicine beforehand as we do with everybody. Our goal is to have it be a pleasant experience as well as a good cosmetic outcome.

Lip plump with Juvederm for a natural, enhanced appearance

Lip plump with Juvederm for a natural, enhanced appearance - Dr. Lupo
Lip plump with Juvederm for a natural, enhanced appearance


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Treating the platysma muscles with Jeuveau helps relax them causing a smoother appearance on the neck

Treating the platysma muscles with Jeuveau helps relax them causing a smoother appearance on the neck - Dr. Lupo


……. Okay!

Jeuveau, like Botox, is a neuromodulator that relaxes overactive muscles that cause wrinkles

Jeuveau, like Botox, is a neuromodulator that relaxes overactive muscles that cause wrinkles - Dr. Lupo


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A quick and painless treatment with Jeuveau reduces lines and lifts/evens out the brows

A quick and painless treatment with Jeuveau reduces lines and lifts/evens out the brows - Dr. Lupo


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FDA approves 'NewTox' Jeauveau - Dr. Lupo says Jeuveau is just recently FDA approved and on the market.

FDA approves NewTox Jeauveau - Dr. Lupo says Jeuveau is just recently FDA approved and on the market.
It’s been nearly two decades since Botox hit the market. It’s becoming the number one cosmetic procedure in the US. But there is a new kid on the block nicknamed "Newtox", so is this competitor better really costless. Medical reporter....


It’s been nearly two decades since Botox hit the market. It’s becoming the number one cosmetic procedure in the US. But there is a new kid on the block nicknamed "Newtox", so is this competitor better really costless. Medical reporter ... up to the people who first tried it five years ago when it was tested right here in .... ... ... ... knows that the sun damage of her use caught of with her.

  • Have your sun ...

  1. Yes we did the oil treatment and laid down on the sun.

  • So, about 10 years ago, she started using botox for the lines in her forehead.

  1. The wrinkles, the makeup gets stuck in there when you have the deep wrinkles.

  • So, five years ago she was one of the first people to try Jeauveau when her dermatologist Dr. Mary Lupo was asked to investigate on it in a clinical trial. Dr. Lupo says that now that Jeauveau is FDA approved, it allows doctors to give patients yet another option.

Dr. Lupo - Perhaps Botox or Dysport or Xeomin didn’t give them everything they wanted, they now have the option to try this new drug which in clinical trial performed beautifully and in studies both in Canada and Europe, it actually outperfomed Botox in head-to-head comparisons.
  • While it outperfomed those other three neuromodulators ... Jeauveau lasted on her a little longer than Botox by about a month more.

  1. No down time, you can see the results the next day. I had no bruising. So, like whatever events I could just go to and not have to worry about coming on lunch break or whatever.

  • Dr. Lupo says results were showing up a few days faster with this product. It’s used to smooth the forehead, the crow’s feet on the corner of the eyes, neck bending, wrinkles around the mouth, chin dimpling and for jaw crunching and raising the eyebrows. A natural look is dependent on having an experienced injector who does not overdo it. And the hope is, this new competitor will drive prices down and get new and even young people to try it to prevent wrinkles before their edged in.

Dr. Lupo - All four of them are extremely safe, extremely effective and have very high patient satisfaction. This is the procedure that even men will do.

  • And ... will keep doing but now with sunscreen every day, for wrinkle free Friday I’m ...

Botox and Jeuveau Injections for Face and Neck

Botox and Jeuveau Injections for Face and Neck
Looking for a quick treat for yourself? Skip the sweets and get a quick face lift with Botox and Jeuveau injections form Dr. Lupo


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Meet one of the countrys leading experts in the field of non-surgical skin rejuvenation.

Lupo Center for Aesthetic and General Dermatology
Mary P. Lupo, M.D. - Connect on Linkedin

Our mission at the Lupo Center is to provide patients with innovative, effective, and ethical care to make each person look and feel their personal best. To fulfill our goal, we provide state-of-the-art medical, surgical, and cosmetic treatments to all patients.

Board-certified dermatologist and clinical professor of dermatology Mary P. Lupo, MD, has been a leader in the field of non-surgical rejuvenation since 1983. She travels internationally to teach her innovative techniques, and her reputation brings in patients from around the country. She started the first formal residency training program for injectables and peels in 1983 at Tulane Medical School and served as past president of the Women’s Dermatologic Society, adjunct professor of dermatology at Tulane, and a founder of Cosmetic Boot Camp. Dr. Lupo holds membership in many prestigious dermatology associations, participates in clinical trials for the approval of new drugs and devices, and acts as an advisor for numerous aesthetic-minded companies.

Dr. Lupo was recently recognized as a trailblazer for women in dermatology and for her dedication to educating dermatology residents and fellows.

She has also received the following awards:

  • 𝐋𝐢𝐟𝐞𝐭𝐢𝐦𝐞 𝐂𝐚𝐫𝐞𝐞𝐫 𝐄𝐝𝐮𝐜𝐚𝐭𝐨𝐫 𝐀𝐰𝐚𝐫𝐝 from the 𝐃𝐞𝐫𝐦𝐚𝐭𝐨𝐥𝐨𝐠𝐲 𝐅𝐨𝐮𝐧𝐝𝐚𝐭𝐢𝐨𝐧 - Recognizes full-time academicians who have dedicated their careers to educating dermatology residents and fellows;

  • 𝐖𝐢𝐥𝐦𝐚 𝐁𝐞𝐫𝐠𝐟𝐞𝐥𝐝, 𝐌𝐃 𝐕𝐢𝐬𝐢𝐨𝐧𝐚𝐫𝐲 and 𝐋𝐞𝐚𝐝𝐞𝐫𝐬𝐡𝐢𝐩 𝐀𝐰𝐚𝐫𝐝 from the 𝐖𝐨𝐦𝐞𝐧'𝐬 𝐃𝐞𝐫𝐦𝐚𝐭𝐨𝐥𝐨𝐠𝐢𝐜 𝐒𝐨𝐜𝐢𝐞𝐭𝐲 - Recognizes dermatologists of national prominence who have been trailblazers for women in some aspect of dermatology.

Dr. Lupo has authored over 90 published articles and book chapters and has spoken on various dermatological topics at nearly 480 national and international meetings and seminars.

Appointment Request:

If you submit an online appointment request, we will contact you to schedule the date and time. All new-patient appointments must be scheduled over the phone.


Success Stories

Lupo Center for Aesthetic and General Dermatology
Review From Casey C.
I’ve been injected by several physicians over the years and Dr Lupo is the best. She gave me an eyebrow lift with filler and it looks like I had surgery.
More Success Stories