A. Perlane is sold by Medicis, the company that also sells the more well known hyaluronic acid filler, Restylane. Perlane is a large particle HA filler that is best used for deeper folds, rather than fine or etched lines. If Perlane is injected too superficially, it causes a blue lump, but it can easily be dissolved with hyaluronidase or the skin can be nicked with a lancet and the excess, superficial material can be gently milked out. Go see an experienced injector and stop suffering with this easily reversible complication.
Q. I have systemic lupus erythematosus. It has never affected my face or skin. I have sun sensitivity, a history of joint pains (now controlled on Plaquenil™)and sometimes some breathing difficulties. I started a new very low carbohydrate diet that I think is really helping my lupus, but I have lost weight in my face and I now look much older (I am 45 and Caucasian). Can I have Restylane injected into my face? Is it safe in patients with lupus?
A. There have been no clinical trials done in order to evaluate the safety and efficacy of fillers in patients with autoimmune conditions. There is a theoretical risk that you would be at increased risk of infection and that the filler would not last as long, but hyaluronic acid fillers such as Restylane/ Perlane or Juvederm would be the relative best choice for injection into patients like you. I have done Restylane in autoimmune patients and can anecdotally report I have seen no complications. I would discuss it with your primary care physician and your dermatologist, but I think it is reasonably safe. By the way, very low carbohydrate diets are anti-inflammatory so I am not surprised your lupus might have improved. Good luck and keep me posted.
More Restylane/Perlane Related Questions
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- New Orleans Restylane - I am only 27 and get a fair amount of sleep but my dark circles have become developed into slight hollowness. I have a great fear of needles going in me that I don't even have my ears pierced. Can you be put to sleep while getting or can you close your eyes while they are injecting near your eyes?
- Restylane Before and After New Orleans - I had Restylane injected 4 months ago while on vacation in California. I have what seems to be the Tyndall effect. How long will it last? Can you advise what laser improves the blue color.
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- What is Restylane New Orleans - 11 months ago, I had a young dermatologist inject me at a teaching hospital. I got the treatment for free, so I did not want to complain, but I have had a blue lump on one side ever since the Perlane was injected. Is there anything that can be done so long after?
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Lupo Center for Aesthetic and General Dermatology
Mary P. Lupo, M.D. - Connect on Linkedin
Our mission at the Lupo Center is to provide patients with innovative, effective and ethical care to make each person look and feel their personal best. To fulfill our goal, we provide state-of-the-art medical, surgical and cosmetic treatments to all patients.
Board certified dermatologist and clinical professor of dermatology Mary P. Lupo, MD has been a leader in the field of non-surgical rejuvenation since 1983. She travels internationally to teach her innovative techniques, and her reputation brings in patients from around the country. She started the first formal residency training program for injectables and peels in 1983 at Tulane Medical School and served as past president of Women’s Dermatologic Society, adjunct professor of dermatology at Tulane and a founder of Cosmetic Boot Camp. Dr. Lupo holds membership in many prestigious dermatology associations, participates in clinical trials for approval of new drugs and devices and acts as an advisor for numerous aesthetic-minded companies.
